To Use. The Herbal Academy neither endorses them nor is in any way responsible for their content. Comfrey is avoided on cuts or puncture wounds for this reason. Comfrey cream contains several active components (substances). Many of those following the folk use of comfrey up to present-day think so. (2013). It also came as a reference to the belief that comfrey can mend broken bones. Ministry of Environment & Forests, Govt. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. root extraction help ease aching joints and muscles? We cover all you need to know in this article. It is easily absorbed to leave your skin feeling fresh, soft and radiant. J Pharm.Belg. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Comfrey is considered likely unsafe to use during pregnancy. Need some help with an order or want to speak to a member of our Customer Services team? 2007;157(21-22):569-574. Comfrey cream may help treat knee osteoarthritis, according to a Cochrane review of topical herbal therapies. 2013;21(6):724-45. 2012;62(6):285-289. Comfrey is considered likely unsafe to use if you are nursing a baby. Complementary Health Approaches for Chronic Pain: What the Science Says. Join rewards for life today and we'll give you 300 points worth 3.00. The Comfrey Controversy: Can and Should One Use Comfrey Internally? Comfrey is likley unsafe to take by mouth. Frost R, Macpherson H, O'meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Comfrey [Online article]. Stickel F, Seitz HK. What alternatives to comfrey cream are there for back pain? Comfrey may be used topically as a cream, ointment, salve, or paste. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. 2004;154(21-22):498-507. Herbal drugs and phytopharmaceuticals. Kucera, M., Barna, M., Horacek, O., Kovarikova, J., and Kucera, A. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study. WMW Wiener Medizinische Wochenschrift, 154(21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. 12 drops black pepper (Piper nigrum) essential oil 2019;24(12):2272. doi:10.3390/molecules24122272, Staiger, Christine. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietician, pharmacist, or healthcare provider. of India has issued Environment Impact Assessment EIA Notification dated 14th September, 2006 for according Environment Clearance(EC) to 8 categories of industries/projects by the Ministry of Environment & Forests, Govt. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. Herbal drugs and phytopharmaceuticals. 4-4-2009;139(13-14):210-211. Company number 02758955 Registered VAT number 211727395. To use on established plants, dilute 1 part comfrey fertilizer in 15 parts water. (2018). Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. However, further well-designed studies are needed. Studies in humans are very limited. This site uses cookies to improve your experience. Rad. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. Store at room temperature away from moisture and heat. Staiger, C. Comfrey: a clinical overview. Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Am J Med 1990;89:547-8. 2013;27(6):811-7. Comfrey is not recommended for children under three years old, as it's not been studied in that population. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. (2004). A significant reduction in pain was observed in the groups using the comfrey product. (2018). British Homeopathic Journal, 90(01), 21-28. https://doi.org/10.1054/homp.1999.0460. Comfrey is not recommended for internal use because of the liver damage caused by its pyrrolizidine alkaloids. Not all possible interactions are listed in this product guide. 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009. Be sure to use comfrey root from a reputable source that has properly identified the species. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. At least three human studies found that the topical use of a cream containing comfrey root extract may safely help with pain, swelling, and mobility symptoms associated with an ankle sprain. After 7 years in this role and a further year working as a drug safety officer in the pharmaceutical industry, Bhupesh joined Holland &Barrett as a Senior Regulatory Affairs Associate in 2019. To reduce the risk of side effects, never apply comfrey cream to broken skin or open wounds as it may be more highly absorbed by the body. Palestrica of the Third Millennium Civilization & Sport, 14(3). You may report side effects to FDA at 1-800-FDA-1088. Wien Med Wochenschr. Comfrey contains toxic substances that cause liver damage, cancer, and death. We answer questions, including what are essential oils? & what can I use them for? in this article. View abstract. , meaning to grow together. To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. Bergamot oil is one of the most popular essential oils, but what is it & what are the benefits of using it? Newer Post Older . After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. This perennial can grow up to 4-feet tall. Spine(Phila Pa 1976). However, it did not affect markers of inflammation or cartilage breakdown over 12 weeks of treatment. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. This is the tincture. Our associates are qualified to advise, visit us online or in store for unparalleled advice. View abstract. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. 2010;44(9):637-41. doi:10.1136/bjsm.2009.058677, Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. 2758955. Understand comfreys contraindications before using it. Ulbricht, C. (2010). Like any new treatment, discontinue use if any irritation occurs. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. Phytother Res. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. 211727395. Click to share on Facebook (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Reddit (Opens in new window), Click to email a link to a friend (Opens in new window), Try A Cooling Herbal Compress for Hot Summer Days, Handmade Floral Paper: A Family-Friendly Project, Making Herbal Preparations 101 Mini Course, Emulsifiers and Preservatives in Botanical Skin Care Products. Mix for about 10 minutes, until nice and whipped. Although topical comfrey has been used for this indication, there's little evidence that it helps and can pose a big risk for nursing babies. Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. This makes quite a thick rich cream good for a body cream and an all healing cream . 12 drops peppermint (Mentha piperita) essential oil An Evidence-Based Reference. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Available for Android and iOS devices. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study. In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). This article discusses the uses and benefits of comfrey cream. Begin mixing on low. It's found in Europe, Asia, and North America. byBhupesh Panchal, Senior Regulatory Affairs Associate, Comfrey oil is a herbal oil that moisturises skin, and thats been used as a healing herb for a long time.1, Since at least the 4th century, people have used comfrey medicinally. In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. For that reason, Ive also included my go-to comfrey cream recipe for achy joints and muscles! Although not all side effects are known, comfrey is thought to be possibly safe when applied to unbroken skin for less than 10 days. https://doi.org/10.1007/s10354-007-0474-y. This site uses cookies to improve your experience. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Aust.Fam.Physician 2008;37(4):235-236. If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. MedlinePlus Medical Encyclopedia. We comply with the HONcode standard for trustworthy health information. Because of the risk of liver toxicity, comfrey cream shouldn't be used with other medicines that may also cause liver damage. Complement Ther Clin Pract. Do not use this product if you have a sensitivity to any of the ingredients. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Jurcu, R., & Jurcu, I. You should never ingest comfrey by mouth. Comfrey can kill. If you're considering using the cream, consult your healthcare provider first. Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Avoid using comfrey together with other herbal/health supplements that can also harm the liver. The Herbal Academy makes neither medical claim, nor intends to diagnose or treat medical conditions. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. This soothing blend of herbal oils contains Comfrey (also known as Knitbone) and Eucalyptus Oil. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Many of those following the folk use of comfrey up to present-day think so. A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. 98% Naturally derived. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Which part of the comfrey plant has the lowest level of pyrrolizidine alkaloids (PAs)? Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. The recipe makes about 6 small jars. You can purchase the Comfrey Ointment at Boots, Tesco, Sainsbury's or Holland & Barrett. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. This is memorable if you have worked with it, and some use this quality to remember comfreys centuries-long useapplying comfrey over bones, bruises, sprains, and minor wounds with the intention to support mending! Comfrey can also contain echimidine, pyrrolizidine alkaloids (PAs), and symphytine, which can damage the liver, are carcinogenic (cancer-causing) and may harm a fetus. Information from this source is evidence-based and objective, and without commercial influence. Food and Drug Administration. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Information offered on Herbal Academy websites is for educational purposes only. Researchers have investigated the effects of comfrey cream on several health conditions. View abstract. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. Metabolism, genotoxicity, and carcinogenicity of comfrey. Jurcu, R., & Jurcu, I. View abstract. 2013;163(3-4):58-64. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. Adv Ther 2005;22(6):681-692. Megan Nunn, PharmD, is a community pharmacist in Tennessee with twelve years of experience in medication counseling and immunization. It may contain small amounts of toxic pyrrolizidine alkaloids. Staiger, C. Comfrey root: from tradition to modern clinical trials. Without overexposure to air or heatand without cross-contaminationthe recipe should last as long as the expiration date of the carrier oils used. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Complement Ther Med. Would you like to win our brilliant Botanical Business Package with nearly $1,000 in prizes? 2020;142:104519. Children, who suffer from these injuries the most, are statistically unlikely to have adverse reactions to comfrey oil when used on scrapes.5, When comfrey was applied topically to animals above where theyd suffered bone fractures, their bones healed at a much-improved rate than animals who hadnt been treated with comfrey.6, Leg ulcers are uncomfortable, prone to infection, and can take a long time to heal. It should only be used in small amounts for short periods as a cream. Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. The groups using the herbal preparations reported a significantly greater reduction in pain and stiffness associated with osteoarthritis of the knee without serious adverse reactions (Smith & Jacobson, 2011). Published 2021 Sep 20. doi:10.1590/1519-6984.249209, Frost R, MacPherson H, O'Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). We cover all you need to know in this article. Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Regul Toxicol Pharmacol. It contains chemicals that are poisonous. 6 Healing Benefits of Comfrey. Phytomedicine. Comfrey also is known as Russian comfrey, knitbone, radix consolidate, bruisewort, blackwort, and slippery root. Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. For topical comfrey cream, look for products labeled as free of pyrrolizidine alkaloids. hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. Add cup of the comfrey tincture and all essential oils to the cooled oil/butter mixture. Comfrey's original name, knitbone, derives from the external use of poultices of its leaves and roots to heal burns, sprains, swelling, and bruises. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. It also covers side effects, interactions, and what to look for. Comfrey has long been used in folk traditions for bruising and abrasions. This could change the effects and side effects of comfrey. British journal of sports medicine, 44(9), 637-641. https://doi.org/10.1136/bjsm.2009.058677, Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. 2 Comfrey cream contains several active components (substances). Oral use of comfrey is not recommended because of potential liver damage. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. 2011;10(3):147-56. doi:10.1016/j.jcm.2011.01.003, Laslett LL, Quinn SJ, Darian-Smith E, et al. Herb & Supplement Guide. Mackinnon, M. In general practice, 'always expect the unexpected'. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. Mosby Elsevier. Scientific studies have shown comfrey oil can help reduce the likelihood leg ulcers will become infected.7, Topical application of comfrey oil has been shown to support the lower and upper back more than methyl nicotinate, the main ingredient in many muscle creams.8. Available for Android and iOS devices. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Therapeutic Research Faculty 2020. Osteoarthritis Cartilage. Kucera, M., Barna, M., Horacek, O., Kalal, J., Kucera, A., and Hladikova, M. Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study.
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